|
KMID : 0363319970180010231
|
|
Journal of Korean Oriental Internal Medicine
1997 Volume.18 No. 1 p.231 ~ p.241
|
|
|
The Cytotoxic effects of several Herbs against human cancer cell-lines
|
|
Jung Hyun-Woo
|
|
|
Abstract
|
|
|
The purpose of this research was to investigate effect of water extract of Euphorbiae Pekinensis Radix and Moutan Cortex Radicis on the proliferation of human cancer cell-lines. The effects of Euphorbiae Pekinensis Radix and Moutan Cortex Radicis on the proliferation of A431, HeLa, MOLT-4, K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay.
The results were as follows;
1. In proliferation of A431, HeLa, MOLT-4 and K562 cell-lines, Euphorbiae Pekinensis Radix and Moutan Cortex Radicis inhibited the proliferation of K562 cells.
2. In the combined effect of Euphorbiae Pekinensis Radix and mitomycin C, Moutan Cortex Radicis and mitomycin C, all herbs stimulated the proliferation of MOL T-4 cells.
3. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis did not inhibited the proliferation of Balb/c 3T3 cells.
4. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis stimulated the proliferation of mouse thymocytes.
5. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis stimulated the proliferation of mouse splenocytes.
6. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis stimulated the proliferation of human lymphocytes
|
|
|
KEYWORD
|
|
|
mitomycin C, A431 cell, HeLa cell, MOLT-4 cell, K562 cell, MTT assay, Lymphocyte
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|